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Quick Details:
Product Name:Lamotrigine
Synonyms:4-triazine-3,5-diamine,6-(2,3-dichlorophenyl)-2;3,5-DIAMINO-6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE;6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE-3,5-DIAMINE;LTG;BW-430C;LAMICTAL;LAMOTRIGIN;LAMOTRIGINE
CAS:84057-84-1
MF:C9H7Cl2N5
MW:256.09
EINECS:281-901-8
Product Categories:APIs;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Glutamate receptor;Amines;Heterocycles;Pharmaceutical intermediate;VANTIN;Other APIs
Melting point:177-181°C
Fp:9ºC
storage temp.:2-8°C
solubility:DMSO: 20 mg/mL at 60 °C, soluble
form:powder
Chemical Properties:White to Cream Coloured Powder
Uses:An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.
Uses:antibacterial
Uses:For the adjunctive treatment of partial seizures in epilepsy and generalized seizures of Lennox-Gastaut syndrome. Also for the maintenance treatment of bipolar I disorder and depression.
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Description
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Lamotrigine, originally marketed as Lamictal and available under many brands worldwide, is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression.
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For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type II.
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Lamotrigine is a synthetic phenyltriazine with anti-epileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.
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COA
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Item | Requirements | Test Results |
Description | A white or almost white crystalline powder | Complies |
Solubility | Soluble in methanol, very slightly soluble in acetone and isopropanol . | Complies |
Melting point | 215°C~ 219°C | 217°C~218°C |
Appearance of solution | 5.0% solution in DMF should be clear | Complies |
Loss on drying | ≤ 0.5% | 0.03% |
Residue on ignition | ≤ 0.1% | 0.04% |
Heavy metals | ≤ 20ppm | Complies |
Residual solvent | Â | Â |
Methanol | ≤ 1000ppm | Complies |
Ethanol | ≤ 1000ppm | Complies |
Any other individual impurity: | ≤ 0.1% | Complies |
Total impurities | ≤ 1.0% | Complies |
Assay | 99.0%-101.0% | 99.70% |
Conclusion | Meets the Requirements |
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Competitive Advantage: | |
Professional Packing | Professional packing with professional materials, and we will give clients several packing way to choose after you contact me through my email |
Quality Assurance  |
Our extensive relationship with manufacturers in China, allow us to bring you the highest quality chemicals, ingredients, and additives at a superior price. The more you buy the more competitive prices you will get. |
Competitive Price  |
Our extensive relationship with manufacturers in China, allow us to bring you the highest quality chemicals, ingredients, and additives at a superior price. The more you buy the more competitive prices you will get. |
In time Delivery: Â |
We promise to deliver each batch of products in time, and with the target that deliver satisfaction rate arrive to 100%. |
Service with heart  |
We Truly Chemical offer specialized logistic service including export declaration, customs clearance and every detail during shipment. This makes us able to offer you one-stop service from the order to the products transported to your hand. Truly Chemical keeps your order in our heart. |
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Quick Details:
Product Name:Lamotrigine
Synonyms:4-triazine-3,5-diamine,6-(2,3-dichlorophenyl)-2;3,5-DIAMINO-6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE;6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE-3,5-DIAMINE;LTG;BW-430C;LAMICTAL;LAMOTRIGIN;LAMOTRIGINE
CAS:84057-84-1
MF:C9H7Cl2N5
MW:256.09
EINECS:281-901-8
Product Categories:APIs;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Glutamate receptor;Amines;Heterocycles;Pharmaceutical intermediate;VANTIN;Other APIs
Melting point:177-181°C
Fp:9ºC
storage temp.:2-8°C
solubility:DMSO: 20 mg/mL at 60 °C, soluble
form:powder
Chemical Properties:White to Cream Coloured Powder
Uses:An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.
Uses:antibacterial
Uses:For the adjunctive treatment of partial seizures in epilepsy and generalized seizures of Lennox-Gastaut syndrome. Also for the maintenance treatment of bipolar I disorder and depression.
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Description
Â
Lamotrigine, originally marketed as Lamictal and available under many brands worldwide, is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression.
Â
For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type II.
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Lamotrigine is a synthetic phenyltriazine with anti-epileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.
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Â
COA
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Item | Requirements | Test Results |
Description | A white or almost white crystalline powder | Complies |
Solubility | Soluble in methanol, very slightly soluble in acetone and isopropanol . | Complies |
Melting point | 215°C~ 219°C | 217°C~218°C |
Appearance of solution | 5.0% solution in DMF should be clear | Complies |
Loss on drying | ≤ 0.5% | 0.03% |
Residue on ignition | ≤ 0.1% | 0.04% |
Heavy metals | ≤ 20ppm | Complies |
Residual solvent | Â | Â |
Methanol | ≤ 1000ppm | Complies |
Ethanol | ≤ 1000ppm | Complies |
Any other individual impurity: | ≤ 0.1% | Complies |
Total impurities | ≤ 1.0% | Complies |
Assay | 99.0%-101.0% | 99.70% |
Conclusion | Meets the Requirements |
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Â
Competitive Advantage: | |
Professional Packing | Professional packing with professional materials, and we will give clients several packing way to choose after you contact me through my email |
Quality Assurance  |
Our extensive relationship with manufacturers in China, allow us to bring you the highest quality chemicals, ingredients, and additives at a superior price. The more you buy the more competitive prices you will get. |
Competitive Price  |
Our extensive relationship with manufacturers in China, allow us to bring you the highest quality chemicals, ingredients, and additives at a superior price. The more you buy the more competitive prices you will get. |
In time Delivery: Â |
We promise to deliver each batch of products in time, and with the target that deliver satisfaction rate arrive to 100%. |
Service with heart  |
We Truly Chemical offer specialized logistic service including export declaration, customs clearance and every detail during shipment. This makes us able to offer you one-stop service from the order to the products transported to your hand. Truly Chemical keeps your order in our heart. |
Mild steel, sometimes referred to as carbon steel or ordinary carbon steel, is defined as having a carbon content of no more than 2% and no other perceptible alloy elements.
This steel is produced on a large scale and is the largest part of the steel production industry. You will be able to find it in various applications, fasteners and fasteners.
Generally, this kind of steel has high strength, high hardness and magnetism, and is usually used in motors and electrical appliances - however, their corrosion resistance is poor, and should not be used in corrosive environment without protective coating or coating.
There are some differences between low-carbon steel and steel, because steel has lower toughness and greater brittleness, and low-carbon steel can be further strengthened by adding carbon.
If you need more information or want to order carbon steel products, such as hexagon Bolts, carriage bolts, flange bolts, U-bolts, union bolts, expansion bolts, threaded rods, please contact us.
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