Caffeic Acid - Making Contraception Safer

Unintended pregnancies are both an injury and a blight to women, but many young people are unwilling to destroy their feelings and do not take any contraceptive measures when they are burning. Until they calm down afterwards, they think of unexpected pregnancy. terrible. Therefore, the emergency contraceptives, with their convenient channels of purchase and easy use, are "of course" the "protective umbrella" that young people are willing to follow, and some women even see it as easy as eating candy.

However, candy is easy to eat, but it is "difficult to swallow." Long-term use of emergency contraceptives can not only lead to female endocrine system disorders, menstrual disorders, bleeding, and can even cause infertility. The most important ingredient of the emergency contraceptives currently on the market is a synthetic progestogen. The chemical name is levonorgestrel, which is rapidly absorbed orally, and is mainly distributed in liver, kidney, ovary, and uterus. Metabolites can be obtained from Excreted in urine and feces, although short-acting contraception, but the contraceptive rate is less than 85%, nausea, vomiting, headache, breast bulging, weight gain, depression, amenorrhea and other symptoms occur after taking. How to develop a new type of emergency contraceptive without side effects has become an important topic in the field of contraception in the world.

Recently, researchers from the Department of Pharmacology, Nanjing Pharmaceutical University discovered the role of caffeic acid in the field of contraception. Through experimentation, they gave orally 60 mg/kg of caffeic acid to the mother and found that the mouse eggs that had been successfully fertilized were killed. Fortunately, after a certain period of time, the mother can have normal fertilization and pregnancy. According to this finding, it can be confirmed that caffeic acid has a significant emergency contraceptive effect, and on the basis of contraception, it will not affect the normal pregnancy of the dehydrated mice. The side effects on the human body are also significantly lower than that of levonorgestrel and other hormone products. More suitable for making emergency contraceptives.

Caffeic acid has extensive antibacterial and antiviral activities and is widely used in medical and health care products. From the point of view of product sources, the chemical synthesis of caffeic acid is relatively simple, the synthesis technology is relatively mature, and the cost is low. It is believed that in the near future, contraceptives containing caffeic acid will quickly occupy the market, so that you can be more assured to "love"!